aminophylline infusion calculation

So 06x106ml Im pretty confident 6ml would be your answer. Therefore 1ml of this infusion solution contains 1mg of aminophylline.

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38 mgkg q 6 hr.

. Per dose 500 mg to be followed by intravenous infusion. Calculate initial dosage using the following equation. 3000 ml ----- 125 mLhr 24 hours Complex Calculations.

Usual range is 6001600 mgday PO in three to four divided doses. 1 mg aminophyllinekg ideal body weighthour as a constant infusion-Obtain a second serum theophylline concentration about one half-life after starting the infusion. Aminophylline infusion rate mghour is multiplied by 24 to yield total daily dose of aminophylline.

Serious side effects may be more likely in older adults. Infusion rates were adjusted based to keep serum theophylline levels within a predefined range in nine studies 21 23 26 28 30 32 34 In two studies 28 32 serum theophylline levels were factored into. 20 to 249 Controlled No adverse reactions are present infusion rate by 25 20 to 249 Controlled Adverse reactions are present Stop infusion for 24 hours subsequent infusion rate at least 25 Adverse reactions symptoms Stop infusion for 24 hours.

Dose mghr x volume in syringe ml Amount in syringe mg Infusion rate. The manufacturer product information should be consulted. Low potassium level--leg cramps constipation irregular heartbeats fluttering in your chest numbness or tingling muscle weakness or limp feeling.

Per dose 5 mgkg to be followed by intravenous infusion. Rate 05 mgkghour rate is half patients weight see table below Dose and rate of aminophylline 1 mgml infusion Patient weight - kg use IBW if patient obese Dose mghr Infusion rate mlhr 40 20 20. This formula allows us to calculate this.

Aminophylline Injection BP may be given by slow intravenous injection or intravenous infusion in glucose injection or sodium chloride injection. B Calculate the Infusion Rate of Aminophylline Solution 1mgml The usual dose range as stated in the BNFC1 and SORT2 guidelines. Under 12 Years 1 milligramkghour 12-17 years 05 to 07 milligramkghour Therefore the maintenance infusion rate range in ml per hour can be calculated as follows Required Dose Weight kg Infusion Rate.

38 mgkg q 4 hr 3 doses. The conventional aminophylline protocol used for group 1 patients consisted of a loading dose of 5 mgkg of body weight administered over 20 minutes followed by an infusion of 04 to 08 mgkgh. 0008 x age in weeks 021 theophylline dosage in mgkghour IV.

Here we need to change to mL 3000. 5mgkg 5mg x 70kg 350mg- add to 100ml of infusion fluid and administer over 20 minutes Maintenance Dose. 500mg per 10ml and want 300mg.

Consider if overdose treatment required. High blood sugar--increased thirst increased urination dry mouth fruity breath odor. I dont remember proper calculations we were taught in nursing school but it makes sense to me.

In this case 500ml500mg 1mlmg. Comments-Careful attention to dose reduction and frequent monitoring of serum theophylline concentrations are required. 38 mgkg q 8 hr.

Using the infusion strength you know that 1ml would administer 1mg of aminophylline so 225ml would administer 225mg. This dose is for patients who have not taken aminophylline in the past 24 hours. The equation for infusion rate calculation is dose stated in prescription milligrams per hour times volume in syringe in millilitres divided by the amount in the syringe in milligrams equals the infusion rate millilitres per hour or.

Therapeutic serum concentrations of theophylline are considered to range from 10 to 20 mcgml and. Aminophylline has a narrow therapeutic index therefore cautious dosage determination is essential. A calculator used to determine the appropriate dosage of Theophylline.

500microgramskghour 500micrograms x 70kg per hour 35000microgramshr 35mg per hour Add 500mg aminophylline to 500ml infusion fluid 1mgml concentration Set rate controlled infusion pump at 35ml per hour. I always clarify every dose calculation with. The results of therapeutic drug monitoring TDM factored into aminophylline dosage calculations in the majority of studies.

Dilute 500mg aminophylline in 500 mL sodium chloride 09 or glucose 5 to give a 1 mgml solution Administration. The loading dose is 57 mgkg based on the ideal body weight for all age groups. The selection by the senior resident of a maintenance dose from this range was based on the patients clinical status according to the monogram principle.

Reduced doses may be needed in patients with risk factors for reduced theophylline clearance eg cardiac or liver dysfunction renal. Court Rules That States Medical Malpractice Act Can Apply to Nonpatients. We need to give 1000 mL of D5W over 24 hours.

For example in non-smoking adults initiation of a constant intravenous theophylline infusion of 04 mgkghr 05 mgkghr as aminophylline at the completion of the loading dose on average will result in a steady-state concentration of. Severe acute asthma in patients not previously treated with theophyllinefor aminophylline. Adult nonsmokers who are otherwise healthy.

This dose mgday is then multiplied by 08adjustment for the ethylenediamine. Of safety even if current dosage is tolerated. Typically after steady-state is achieved with the intravenous aminophylline infusion the following procedure is used to calculate the oral theophylline dose.

Loading doses should be administered over 30 minutes at a rate not to exceed 21 mghr and should be calculated using ideal body weight. For example in non-smoking adults initiation of a constant intravenous theophylline infusion of 04 mgkghr 05 mgkghr as aminophylline at the completion of the loading dose on average will result in a steady-state concentration of. 1000 mL ----- mLhr 416 mlhr 42 mlhr for our pump rate 24 hours We need to give 3L of NS over 24 hours.

Lets use the same examples. 38 mgkg q 6 hr 2 doses. We would therefore set the infusion rate as 225mlhour 225mg1 where 1 is the strength of the dosage in mlmg.

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